Table 6.

For male study participants: Liver-specific characteristics (mean (±SD) or median (25th to 75th percentile) data) according to six different alcohol consumption groups.

Variable	Groups of total alcohol consumption
Male	No consumption 0 g/d ethanol	Very low consumption > 0.0 - 12.0 g/d ethanol	Low consumption > 12.0 - 24.0 g/d ethanol	Medium consumption > 24.0 - 36.0 g/d ethanol	High consumption > 36.0 - 48.0 g/d ethanol	Very high consumption > 48.0 g/d ethanol	Pa	FDR-Pb
N	312	188	104	121	82	117	-	-
Alanine Aminotransferase (U/L)	10.0 (8-13)	10.0 (8-13)	10.0 (8-13)	11.0 (9-14)	11.0 (9-14)	11.0 (9-16)	<0.001	0.001
Aspartate Aminotransferase (U/L)	13.0 (10-20)	13.5 (10-21)	13.0 (9.25-20)	14.0 (11-21.2)	14.0 (10-20)	15.0 (11-22)	0.051	0.062
De Ritis ratio	1.35 (1.07-1.72)	1.3 (1.07-1.7)	1.33 (1-1.69)	1.38 (1.08-1.67)	1.33 (1.04-1.67)	1.33 (1.08-1.59)	0.936	0.936
γ-Glutamyltransferase (mg/dl)	17.0 (11-28)	18.0 (12-29)	19.0 (13-31)	18.0 (11-31)	21.0 (13-37)	27.0 (16-46.8)	<0.001	<0.001
Mean corpuscular volume (fL)	88.6 (85.9-91.4)	88.8 (86.3-91.7)	90.0 (86.9-93.2)	89.4 (86.8-92.6)	89.7 (86.8-92.3)	90.8 (87.9-93.8)	<0.001	<0.001
Fibrinogen (mg/L)	386 (325-465)	368 (311-444)	365 (319-451)	360 (310-427)	386 (321-467)	388 (327-458)	0.006	0.009
Fatty liver index	55.2 (34.2-76.6)	54.1 (34-74.4)	58.9 (36.6-80.8)	56.3 (37-75)	60 (37.9-76.7)	68.8 (44.1-85.5)	<0.001	<0.001
Interleukin 6 (ng/L)	3.39 (1.89-6.81)	3.06 (1.76-5.52)	3.16 (1.94-6.55)	3.04 (1.75-5.3)	3.32 (1.84-6.46)	3.46 (1.98-7.46)	0.010	0.014
Mean platelet volume (fL)	8.9 (8.3-9.6)	8.8 (8.2-9.5)	8.9 (8.2-9.7)	9.1 (8.5-9.7)	9.0 (8.4-9.6)	9.1 (8.3-9.7)	0.013	0.018

^aANOVA (non-normally distributed variables were analysed by Kruskal-Wallis rank sum test) or Chi square test.

^bp value after FDR correction.