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Antitumor mechanism of compound 17c. (A, B) Change in PDEδ downstream proteins in SW480 cancer cells induced by compound 1 and compound 17c for 24 h. The Western blot analysis was repeated at least three times. (C, D) Compound 17c induced apoptosis of SW480 cancer cells after 24 h of treatment. All bar graphs present the mean ± SD.
