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. 2022 Feb 14;40(13):2062–2067. doi: 10.1016/j.vaccine.2022.02.025

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Fig. 1 — Distribution of IgG(S-RBD) titers by the fever grade after the second vaccination, according to sex and age. Box-and-whisker plots for distribution of IgG(S-RBD) titers. A box represents interquartile range and a horizontal line and circle in a box represents median and mean, respectively. A vertical line represents the range, excluding outliers. A circle out of a box represents an outlier. Differences in the GMTs of IgG(S-RBD) among the grades of fever were analyzed using ANOVA.