Figure 1.

Flowchart of the study population in total and by Olink panels. Individuals were excluded from a panel if their sample failed Olink’s quality control or more than 15% of the proteins in that panel were below the lower limit of detection (LOD). Individuals were also excluded if they were missing information on chronotype. Proteins were excluded if they were below the LOD in more than 15% of the samples. Final study population comprised 2,436 individuals and 242 proteins. CVD, cardiovascular disease.