TABLE 3.
Serum and IgG N‐glycans in ITP patients with PLT≥30 × 109/L and PLT<30×109/L
| Peak or glycosylation | Serum | IgG | ||||
|---|---|---|---|---|---|---|
|
PLT≥30 × 109/L (n = 39) |
PLT<30 × 109/L (n = 22) |
P1 |
PLT≥30 × 109/L (n = 20) |
PLT<30 × 109/L (n = 14) |
P2 | |
| Peak 1 | 7.60 ± 2.37 | 6.96 ± 2.85 | 0.347 | 29.10 ± 7.83 | 27.42 ± 7.19 | 0.530 |
| Peak 2 | 1.12 ± 0.36 | 1.08 ± 0.44 | 0.683 | 4.57 ± 1.61 | 4.21 ± 1.72 | 0.535 |
| Peak 3 | 6.12 ± 1.39 | 5.47 ± 1.29 | 0.080 | 21.58 ± 2.84 | 22.15 ± 3.61 | 0.609 |
| Peak 4 | 5.36 ± 0.90 | 5.14 ± 0.80 | 0.330 | 14.51 ± 1.93 | 14.57 ± 2.88 | 0.947 |
| Peak 5 | 41.51 ± 4.42 | 43.62 ± 4.01 | 0.069 | 5.26 ± 1.26 | 5.17 ± 1.26 | 0.828 |
| Peak 6 | 19.32 ± 2.96 | 18.23 ± 2.79 | 0.162 | 22.10 ± 7.91 | 23.44 ± 5.14 | 0.553 |
| Peak 7 | 5.56 ± 1.12 | 4.95 ± 1.24 | 0.052 | 2.88 ± 1.29 | 3.05 ± 1.49 | 0.733 |
| Peak 8 | 8.04 ± 2.03 | 8.48 ± 2.94 | 0.490 | ‐ | ‐ | ‐ |
| Peak 9 | 1.71 ± 1.03 | 2.24 ± 1.29 | 0.080 | ‐ | ‐ | ‐ |
| Peak 9p | 1.04 ± 0.38 | 1.06 ± 0.54 | 0.842 | ‐ | ‐ | ‐ |
| Peak 10 | 0.27 ± 0.08 | 0.34 ± 0.14 | 0.051 | ‐ | ‐ | ‐ |
| Peak 11 | 2.16 ± 0.70 | 2.20 ± 0.76 | 0.817 | ‐ | ‐ | ‐ |
| Fucosylation | 46.40 ± 5.81 | 43.22 ± 5.71 | 0.043* | 94.74 ± 1.26 | 94.83 ± 1.26 | 0.828 |
| Galactosylation | 91.09 ± 2.65 | 91.73 ± 3.08 | 0.396 | 66.33 ± 8.97 | 68.37 ± 7.89 | 0.498 |
Data were expressed as means ± standard deviation (SD); PLT: platelet counts; P1: comparison of serum N‐glycans between ITP with PLT≥30 × 109/L and PLT<30 × 109/L; P2: comparison of IgG N‐glycans between ITP with PLT≥30 × 109/L and PLT<30 × 109/L. * p < 0.05, the difference is statistically significant.