TABLE 2.
Differential metabolites identified from metabolomics profiling
| Metabolite name | HER2 | NC | FC | VIP | Mode |
|---|---|---|---|---|---|
| Dihydrotestosterone | 1601 | 680 | 2.35 | 1.12 | POS |
| Hypoxanthine | 2008 | 532 | 3.78 | 1.40 | POS |
| Pregnenolone | 1849 | 697 | 2.65 | 1.24 | POS |
| Monoolein | 1775 | 268 | 6.61 | 1.19 | POS |
| N1‐Acetylspermine | 1621 | 337 | 4.81 | 1.09 | POS |
| L‐Arginine | 1516 | 29 | 51.58 | 1.44 | POS |
| Citrazinc acid | 648 | 1850 | 0.35 | 1.34 | POS |
| 8,15‐DiHETE | 1919 | 631 | 3.04 | 1.69 | NEG |
| 9‐KODE | 1770 | 669 | 2.65 | 1.34 | NEG |
| Arachidonic acid | 2232 | 573 | 3.89 | 1.69 | NEG |
| dehydroxynocardamine | 1430 | 849 | 1.68 | 1.03 | NEG |
| FA 18:4+2O | 1738 | 670 | 2.59 | 1.30 | NEG |
| gamma‐Linolenic acid | 1822 | 635 | 2.87 | 1.39 | NEG |
| Hexose | 1501 | 698 | 2.15 | 1.33 | NEG |
| L‐Phenylalanine | 1285 | 782 | 1.64 | 1.03 | NEG |
| LPC 16:0; PlaSMA ID‐1486 | 1369 | 827 | 1.66 | 1.01 | NEG |
| LPC 18:1; PlaSMA ID‐1563 | 1458 | 838 | 1.74 | 1.07 | NEG |
| LPC 18:3; PlaSMA ID‐1545 | 1853 | 689 | 2.69 | 1.28 | NEG |
| LPE 18:1; PlaSMA ID‐1334 | 1645 | 870 | 1.89 | 1.03 | NEG |
| Myristic acid | 1681 | 748 | 2.25 | 1.08 | NEG |
| Phosphatidylethanolamine lyso 16 | 1802 | 810 | 2.22 | 1.22 | NEG |
| Phosphatidylethanolamine lyso 17 | 1553 | 867 | 1.79 | 1.01 | NEG |
| Phosphatidylethanolamine lyso 18 | 1486 | 674 | 2.20 | 1.30 | NEG |
| PFAP‐diPAP | 276 | 1583 | 0.17 | 1.83 | NEG |
Abbreviations: FC, Fold change; NC, Normal control; NEG, Negative; POS, Positive; VIP, Variable important in projection.