Table 4.

Risk factors associated with unplanned hospitalization during chemotherapy.

	Unplanned hospitalization during chemotherapy		Univariate		Multivariable
	No (%) (N = 134)	Yes (%) (N = 65)	OR (95% CI)	P-value	OR (95% CI)	P-value
Age (years) (mean (SD))	73.3 (6.43)	74.7 (6.96)	1.03 (0.98-1.08)	0.16	1.03 (0.98-1.09)	0.23
Sex, n (row%)
Male	67 (76.1%)	21 (23.9%)	1.0		1.0
Female	67 (60.4%)	44 (39.6%)	2.10 (1.13-3.90)	0.02	1.80 (0.89-3.65)	0.10
Cancer type, n (row%)
Colorectal	64 (75.3%)	21 (24.7%)	1.0		1.0
Gastric/esophageal	29 (56.9%)	22 (43.1%)	1.92 (1.03-3.56)	0.03	2.15 (0.90-5.16)	0.09
Pancreatic/hepatobiliary	41 (63.1%)	22 (34.9%)	1.63 (0.80-3.34)	0.18	1.78 (0.74-4.29)	0.20
Cancer stage, n (row%)
I/II/III	63 (75.9%)	20 (24.1%)	1.0		1.0
IV	71 (61.2%)	45 (38.8%)	2.00 (1.07-3.74)	0.03	1.57 (0.78-3.18)	0.21
Number of chemotherapy agents, n (row%)
Single	46 (65.7%)	20 (30.3%)	1.0		1.0
Poly	88 (66.2%)	45 (33.8%)	1.18 (0.62-2.22)	0.62	1.75 (0.75-4.10)	0.20
Hearing problem, n (row%)
No	105 (70.9%)	43 (29.1%)	1.0		1.0
Yes	28 (56.0%)	22 (44.0%)	1.92 (1.00-3.72)	0.05	2.05 (0.95-4.43)	0.07
Missing	1	0
History of heart disease, n (row%)
No	114 (74.0%)	40 (26.0%)	1.0		1.0
Yes	20 (44.4%)	25 (55.6%)	3.56 (1.79-7.10)	<0.001	2.48 (1.13-5.42)	0.02
Daily medications, n (row%)
0-4	90 (75.0%)	30 (25.0%)	1.0		1.0
5+	42 (56.8%)	32 (43.2%)	2.29 (1.23-4.24)	0.008	1.88 (0.94-3.75)	0.07
Missing	2	3
Serum albumin, n (row%)
Normal ([3.5 g/dL, 5.5 g/dL])	95 (72.0%)	37 (28.0%)	1.0		1.0
Low (<3.5 g/dL)	39 (58.2%)	28 (41.8%)	1.84 (1.00-3.41)	0.05	1.64 (0.81-3.32)	0.17

Multivariable ORs were obtained from models with all variables adjusted in the model.