Table 1.
Characteristics of Study Population for Plasma Metabolomics
| Characteristic | PDR (n = 88) | Control (n = 51) | P Value |
|---|---|---|---|
| Age* (y) | 55.3 ± 9.7 | 67.0 ± 8.1 | <0.001 |
| Gender† (male/female), n | 44/44 | 20/31 | 0.219 |
| FBG‡ (mmol/L) | 6.3 ± 3.5 | 5.0 ± 1.2 | <0.001 |
| Creatinine‡ (µmol/L) | 69 ± 37 | 64 ± 25 | 0.235 |
| Urea‡ (mmol/L) | 6.6 ± 3.0 | 5.3 ± 1.7 | <0.001 |
| TC* (mmol/L) | 4.68 ± 1.31 | 4.78 ± 0.96 | 0.637 |
| TG‡ (mmol/L) | 1.33 ± 0.78 | 1.40 ± 1.29 | 0.293 |
| HTN† (yes/no), n | 44/44 | 22/29 | 0.435 |
| CAD† (yes/no), n | 3/85 | 1/50 | 1.000 |
| DLD† (yes/no), n | 40/48 | 30/21 | 0.129 |
| Other diabetic complications,† n | 4/84 | 0/51 | 0.296 |
| Treatments, n | |||
| Anti-VEGF† (yes/no) | 26/62 | 0/51 | <0.001 |
| Antidiabetic medications† (yes/no) | 88/0 | 0/51 | <0.001 |
| Antihypertension† (yes/no) | 43/45 | 21/30 | 0.381 |
Both age and TC data are represented as mean ± SD. FBG, creatinine, urea, and TG are represented as median ± interquartile range. CAD, coronary artery disease; DLD, dyslipidemia; HTN, hypertension; TC, total cholesterol; TG, triglyceride.
*I
ndependent samples t-test.
†
Chi-square test.
‡
Mann–Whitney U test.