Table 3.
Discriminatory Metabolites Shared by Vitreous and Plasma in Patients With PDR
| Variation Trend | ||||
|---|---|---|---|---|
| No. | Metabolite | ID | Plasma | Vitreous |
| 1 | Pipecolic acid | C00408 | ↓ | ↓ |
| 2 | Pantetheine | C00831 | ↑ | ↑ |
| 3 | Pyroglutamic acid | C01879 | ↑ | ↓ |
| 4 | Alpha-N-phenylacetyl-L-glutamine | C04148 | ↑ | ↑ |
| 5 | (24R)-Cholest-5-ene-3-beta,24-diol | C15497 | ↑ | ↑ |
Untargeted metabolomics was performed in both plasma and vitreous samples, and there were 15 and 76 discriminating metabolites, respectively. Among these discriminating metabolites, five were shared by vitreous and plasma. The variation trends of them in the PDR group are listed.