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. 2022 Feb 14;20:13. doi: 10.1186/s12969-022-00673-y

Table 1.

Demographic and clinical characteristics

All patients n = 32 (%) Thrombosis n = 9 (%) Non-thrombotic n = 23 (%) P value
 Sex (female/male) 21/11 4/5 17/6 0.11
 Age (years) 11.7 (1–15) 12.2 (1–15) 11.5 (6–15) 0.93
 Evolution time (weeks) 16 (1–108) 7.5 (1–28) 19 (1–108) 0.21
 Hematologic 29 (90%) 7 (78%) 22 (96%)
 Thrombocytopenia 22 (67%) 7 (78%) 15 (65%) 0.49
 AIHA 13 (41%) 2 (22%) 11 (48%) 0.18
 LAHP 2 (6%) 0 2 (9%) 0.36
 Dermatologic 23 (72%) 7 (78%) 16 (70%)
 Livedo reticularis 20 (63%) 7 (78%) 13 (57%) 0.26
 Raynaud's phenomenon 8 (25%) 2 (22%) 6 (26%) 0.82
 Skin ulcers 2 (6%) 0 2 (9%) 0.36
 Neurologic 5 (16%) 1 (11%) 4 (17%)
 Migraine 3 (9%) 1 (11%) 2 (9%) 0.83
 Cognitive impairment 3 (9%) 1 (11%) 2 (9%) 0.83
 Epilepsy 1 (3%) 1 (11%) 0 0.10
 Chorea 1 (3%) 0 1 (4%) 0.52
 Renal 4 (13%) 3 (33%) 1 (4%)
 Nephrotic síndrome 1 (3%) 1 (11%) 0 0.10
 Nephritic syndrome 3 (9%) 2 (22%) 1 (4%) 0.11
Clinical profile
 T 1 (3%) 1 (11%) 0
 H 6 (19%) 0 6 (26%)
 R 1 (3%) 1 (11%) 0
 C 1 (3%) 0 1 (4%)
 H + C 16 (50%) 5 (55%) 11 (48%)
 H + N 1 (3%) 0 1 (4%)
 H + C + R 2 (6%) 1 (11%) 1 (4%)
 H + C + N 3 (9%) 0 3 (13%)
 H + C + N + R 1 (3%) 1 (11%) 0

LAHP Lupus anticoagulant with hypoprothrombinemia syndrome, AIHA Autoimmune hemolytic anemia, T Thrombosis, H Hematologic, R Renal, C Cutaneous, N Neurologic