Table 2.

Association of TXNIP cg19693031 methylation and GLUT1 rs841853 with fasting blood glucose

	β	p-value
TXNIP cg19693031 (ref: ≥ Q3)
Q2–Q3	− 0.0236	0.965
Q1–Q2	1.0317	0.058
< Q1	1.3336	0.019
P for trend		0.005
GLUT1 rs841853 (ref: CC)
CA + AA	− 0.4576	0.232
Sex (ref: Women)
Men	2.4784	< .001
Age	0.1935	< .001
BMI	0.1647	0.006
Cigarette smoking (ref: No)
Yes	0.7118	0.166
Alcohol drinking (ref: No)
Yes	1.2013	0.086
Triglyceride	0.0031	0.146
HDL-C	− 0.0338	0.037
LDL-C	0.0094	0.112
Hypertension (ref: No)
Yes	0.3245	0.540
Exercise (ref: No)
Yes	− 0.3790	0.362
Tea intake (ref: No)
Yes	0.1308	0.742
Coffee intake (ref: No)
Yes	− 0.2297	0.564
Vegetarian diet (ref: No)
Yes	− 1.9887	0.004
TXNIP cg19693031*SLC2A1 rs841853	p-value = 0.036

TXNIP thioredoxin-interacting protein, GLUT1 glucose transporter 1, β beta coefficient, ref reference, BMI body mass index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, *: interaction term