Table 2.

Serum neutralisation test after the CyHV-3 challenge.

SNT	Experimental group
Time point	CB	CD	CVB	CVD	KB	KD	KVB	KVD
2 dpc	40 ± 24	24 ± 9	1952 ± 1987*	1440 ± 2104*	152 ± 155	156 ± 151	1024 ± 251*	1504 ± 2066*
7 dpc	20 ± 0	36 ± 26	968 ± 1003*	2688 ± 2401*	80 ± 49	56 ± 59	928 ± 511*	1472 ± 1052*
14 dpc	21 ± 0	20 ± 0	608 ± 429*	640 ± 1078*	§	§	1728 ± 2130*	1856 ± 2029*
28 dpc	22 ± 0	20 ± 0	1792 ± 2081*	704 ± 351*	§	§	1920 ± 1810*	2368 ± 1805*

The description of experimental groups: CB – BSA, non-vaccinated, unchallenged control, CD – defensins, non-vaccinated, unchallenged control, CVB – BSA, vaccinated, unchallenged control, CVD – defensins, vaccinated, unchallenged control, KB - BSA non-vaccinated, CyHV-3 challenged, KD – defensins non-vaccinated, CyHV-3 challenged, KVB – BSA, vaccinated, CyHV-3 challenged, KVD – defensins, vaccinated, CyHV-3 challenged. The results are presented as a mean ± SD of the highest serum dilution inactivating the CyHV-3. § indicates that fish from these experimental groups had to be removed before the time point due to pathological changes.* indicates statistical significant difference when compared with the control at p < 0.05. Statistical analysis was performed with two-way ANOVA with multiple comparisons test performed with the Holm-Sidak method.