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Voxel-based analysis of IC and ISO signal fraction maps (A,B). Lower IC and higher ISO values were found in MCI in several white matter regions and tracts. The clusters and the coordinates are in MNI152 space. Overlapped clusters by FWE < 0.05 and | g| > 0.82 (C). Significant voxel-wise Spearman’s correlations were found between IC and MoCA scores in the MCI cohort (D).
