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. 2022 Jan 31;9:812422. doi: 10.3389/fcell.2021.812422

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Copyright © 2022 Cai, Liang, Zhan, Zeng, Lin, Xu, Xue, Xu, Chai, Mao, Song, Han, Xiao, Song and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anti-tumor immunity and intrinsic immune escape associated with FRGPI. Spearman correlation coefficients and associated p-value of FRGPI with (A) FPI, (B) stromalScore, (C) immuneScore, (D) the expression of PD-L1, (E) TMB score, (F) MSI score, (G) mRNAsi, (H) mDNAsi are shown. r, Spearman coefficient; ns, no significance; *p < 0.05; **p < 0.01; ***p < 0.001. (I) Different immune cell infiltration between high and low FRGPI group, and the correlation between FRGPI and immune cells infiltration. ns, no significance; *p < 0.05; **p < 0.01; ***p < 0.001; blue, positive correlation; red, negative correlation.