Table 1.
Risk Factor | Primary Route of Exposure | Exposure Limit/Maximum Contaminat Level | Extrapolated Daily Dose in Mice | Extrapolated Daily Dose in Rats |
Paraquat | Inhalation | 0.1 mg/m3 † | 1.22 mg/m3 | 0.6 mg/m3 |
Drinking Water | 20 ppb | 245μg/kg | 123μg/kg |
†Time Weighted Average: 8-hour total weight average, particulate size dependent. Inhalation dose calculated using the fixed allometric exponent: Xh = Xa (Ma/Mh)1 - .67 without Uncertainty Factors [47], however dosage is dependent on particulate size and duration of exposure. Oral dose calculated using the U.S. FDA conversion guidelines, Human Equivalent Dose = animal dose in mg/kg x (animal weight in kg / human weight in kg)0.33 [46].