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. 2022 Jan 21;12(1):341–351. doi: 10.3233/JPD-212876

Table 3.

SNpc neuron densities and correlations with estimated PD risk

Overall correlation with PD risk probability (n = 134) Neuron counts by case status mean neurons/mm3 with 95%CI
Diagnosed with PD (n = 31) Controls
LB-Yes (n = 78) LB-No (n = 25)
Dorsomedial quadrant –0.16, p = 0.10 9.1 (6.9–11.3) 15.3 (13.5–17.1) 19.4 (15.7–23.1)
Ventromedial quadrant –0.28, p < 0.01 8.6 (6.2–11.0) 15.1 (13.2–17.0) 19.5 (15.9–23.1)
Dorsolateral quadrant –0.08, p = 0.38 7.8 (6.0–9.6) 10.4 (9.1–11.7) 12.7 (9.5–15.9)
Ventrolateral quadrant –0.23, p < 0.05 5.3 (3.6–7.0) 15.8 (13.8–17.8) 20.2 (17.5–22.9)
Total Neuron Density –0.24, p < 0.01 7.7 (6.0–9.4) 14.3 (12.9–15.7) 18.2 (15.6–20.8)