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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Proc Nutr Soc. 2021 Apr 26;80(3):319–326. doi: 10.1017/S0029665121000914

Figure 1. Vitamin E interactions with lipid peroxidation and antioxidants.

Figure 1.

Vitamin E intercepts peroxyl radicals (LOO.), but becomes a radical itself (vitamin E.), which is reduced by VitC, oxidizing it. Glutathione reduces the VitC. and becomes oxidized itself. The GSSG is then enzymatically reduced by glutathione reductase. Thus, the reversal of the oxidation entire process is energy (NADPH) dependent.