Kaplan-Meier curves showing cumulative probability of disease progression from aMCI to dementia. Classification model is developed by applying logistic regression (A) and RUSBoost models (B) to demographics, APOE ε4, and neuropsychological tests. AD, Alzheimer’s disease; aMCI, amnestic mild cognitive impairment; APOE, apolipoprotein E; CN, cognitively normal