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. 2021 Jun 10;21(1):e12750. doi: 10.1111/gbb.12750

FIGURE 1.

FIGURE 1

Complete Deletion mice have altered associated fear responses in a conditioned fear task. (A) Overview of the conditioned fear task protocol. (B) Day 1. CD and WT mice show increased freezing with subsequent footshock deliveries. (C) All mice increased freezing in the context associated with the footshock. Baseline is the average of the first 2 min of Day 1. Context is the average of the first 2 min of Day 2. Black bars indicate the mean average percent freezing. Data points of individual mice are connected. (D) Day 2. All mice increased freezing to context relative to Day 1 baseline, although CD mice freeze less than WT mice. (E) Day 3. CD mice have significantly decreased freezing relative to WT mice during minute 4 of tone delivery (p = 0.036). WT: n = 10; CD: n = 10. Connected data points in B, D and E are means ± SEM. Individual scores are represented by colored circles in the background