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. 2022 Feb 14;29:12. doi: 10.1186/s12929-022-00796-0

Fig. 1.

Fig. 1

Obesity-related physiological states, immune response and cancer development. Comparison between underweight/lean, overweight/mild obesity and obese phenotypes, regarding their physiological states, immune responses and cancer development. While both extremes—underweight and obese—show poor survival and disadvantages regarding cancer development and progression, mild obesity, in overweight patients, has been described as a protective phenotype, allowing for improved immunotherapy response and survival of cancer patients