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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Obesity (Silver Spring). 2021 Feb 16;29(4):713–720. doi: 10.1002/oby.23112

Figure 1: TM5441 attenuates diet-induced obesity and hepatic steatosis in mice.

Figure 1:

A) Body weight change (%), B) average daily food consumption (g/mouse/day), C) representative H&E and trichrome-stained liver sections and F4/80-stained adipose tissue sections with associated quantification, D) hepatic triglyceride content (mg trig per gram liver), and E) plasma ALT level (U/L) in C57BL/6J mice fed a HFHS diet for 16 weeks or a HFHS diet for 8 weeks followed by a HFHS diet supplemented with TM5441 for an additional 8 weeks (HFHS+TM). Values expressed as mean (n=8) ± SD, *p<0.05.