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. 2022 Jan 31;16:725478. doi: 10.3389/fnins.2022.725478

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Copyright © 2022 Zhang, Wang, Chen, Sun, Chen, Tan, Xia, Zhang, Lu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The joint association of weighted genetic risk and sleep pattern with CKD among 370,671 European ancestry participants. The vertical line indicates the reference value of 1. Multivariable model was adjusted for age, sex, ethnicity (White/others), education (university or college degree/others) and the Townsend index (continuous), smoking status (current, ever, never), drinking status (drinks, continuous variable), physical activity (at goal or not), overweight and obesity (BMI ≥ 25 kg/m2), systolic blood pressure, diabetes (yes/no), use of blood pressure-lowering medications (yes/no) and use of diabetes medications (yes/no). CKD, chronic kidney disease; CI, confidence interval; OR, Odds Ratio.