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. 2022 Jan 31;16:725478. doi: 10.3389/fnins.2022.725478

TABLE 2.

Multivariable-adjusted Odds Ratio (95% CIs) for CKD by low-risk sleep factors.

% of 370,671 participants Model 1 Model 2 Model 3 Population attributable risk,%
Sleep 7–8 h/day 68.4 0.83 (0.79, 0.88)* 0.84 (0.80, 0.89)* 0.88 (0.84, 0.93)* 4.8 (2.9 to 6.8)
Early chronotype 62.7 0.97 (0.92, 1.02) 0.98 (0.93, 1.03) 1.00 (0.94, 1.05) 0.2 (−1.7 to 2.1)
Never/rarely insomnia 24.6 0.88 (0.82, 0.94)* 0.88 (0.83, 0.94)* 0.91 (0.86, 0.97)* 8.5 (3.7 to 13.1)
No self-reported snoring 62.8 0.90 (0.85, 0.95)* 0.90 (0.86, 0.95)* 0.99 (0.94, 1.05) 0.4 (−1.7 to 2.5)
No frequent daytime sleepiness 76.5 0.80 (0.76, 0.85)* 0.82 (0.78, 0.87)* 0.87 (0.82, 0.91)* 1.1 (0.4 to 1.7)
Five healthy behaviors 6.2 0.70 (0.62, 0.80)* 0.71 (0.63, 0.81)* 0.79 (0.69, 0.90)* 17.1 (7.7 to 26.3)

Model 1 was adjusted for age, sex, ethnicity (White/others), education (university or college degree/others) and the Townsend index (continuous). *P < 0.05. Model 2 was further adjusted for smoking status (current, ever, never), drinking status (drinks, continuous variable), physical activity (at goal or not). Model 3 was adjusted for terms in model 2 and overweight and obesity (BMI ≥ 25 kg/m2), systolic blood pressure, diabetes (yes/no), use of blood pressure-lowering medications (yes/no) and use of diabetes medications (yes/no). Five sleep behaviors were included simultaneously in the model.