Table 1. Effects of khat on average escape latency, swim path-length, swimming speed and thigmotaxis in rats.
Group | Parameters | |||
---|---|---|---|---|
Escape latency(s) (M±SEM) | Swim Path length(cm) (M±SEM) | Swim speed(cm/s) (M±SEM) | Thigmotaxis (s) (M±SEM) | |
T80W | 19.00±2.31 | 416.67±59.37 | 21.83±1.79 | 9.67±.1.17 |
KESA 300 mg/kg | 15.17±.75 | 703.17±38.65** | 46.48±1.89*** | 6.50±34*** |
KESC 100 mg/kg | 24.50±1.09 | 801.33±41.23*** | 32.97±1.99*** | 18.83±.79*** |
KESC 200 mg/kg | 34.83±2.46*** | 841.67±63.61*** | 24.19±1.03 | 23.83±2.01*** |
KESC 300 mg/kg | 30.83±1.54** | 822.50±35.48*** | 26.78±.72 | 21.67±1.20*** |
KHJ 2.5 mL/kg | 28.83±2.63* | 775.17±58.97*** | 27.13±1.03 | 20.50±1.57*** |
Each point represents the mean ± SEM of escape latency, swim path-length, swim speed and thigmotaxis in rats (n = 6/ group) that received T80W, KESC (100 mg/kg, 200 mg/kg and 300 mg/kg), KESA (300 mg/kg) and KHJ 2.5 mL/kg.
***p < 0.001, **p < 0.01 and *p < 0.05 when each group of rats was compared with rats that received T80W.
KESC: khat extract subchronic, KESA: khat extract subacute, KHJ: khat juice.