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(A) Serial cross-sectional tumor dimensions while the patient received AMG510. (B) All samples were acquired either before the patient went on study (pre-AMG510) or during the rapid autopsy 6 weeks after stopping the drug (post-AMG510). All nonadjacent normal tissues were at least 1 cm from the tumor margin and confirmed by a pathologist to be free of tumor. (C) An illustration of the locations of tumors sampled for the study.
