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. 2022 Feb 9;17:603–616. doi: 10.2147/IJN.S347506

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© 2022 Wei et al.

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Biocompatibility evaluation of HA NPs in vitro and in vivo. (A) The counts’ changes of Red blood cell, White blood cell, Neutrophil, Lymphocyte Platelet, Hemoglobin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea (UREA) and creatinine (CREA), creatine kinase (CK) and lactate dehydrogenase (LDH-1) (n=6). (B) H&E staining of vital organs (heart, liver, spleen, lung, kidney) was used to assess the systemic toxicity of HA NPs.