Table 3.
Top 10 enriched biological processes from the gene ontology (GO) analysis.
| Category | Term | Molecule name | P-value | Gene |
|---|---|---|---|---|
| GOTERM_BP | GO:0099528 | G protein-coupled neurotransmitter receptor activity | 2.0 E-11 | ADRB1, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
| GOTERM_BP | GO:1904999 | positive regulation of leukocyte adhesion to arterial endothelial cell | 2.5 E-6 | ALOX5, TNF |
| GOTERM_BP | GO:0004935 | adrenergic receptor activity | 2.0 E-11 | ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRB1, ADRB2 |
| GOTERM_BP | GO:0001993 | regulation of systemic arterial blood pressure by norepinephrine-epinephrine | 2.0 E-11 | ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
| GOTERM_BP | GO:0001996 | positive regulation of heart rate by epinephrine-norepinephrine | 2.0 E-11 | ADRA1A, ADRA1B, ADRA1D, ADRB1 |
| GOTERM_BP | GO:0002025 | norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure | 2.0 E-11 | ADRB1, ADRB2 |
| GOTERM_BP | GO:0004936 | alpha-adrenergic receptor activity | 2.0 E-11 | ADRA1A, ADRA1B, ADRA1D, ADRA2A |
| GOTERM_BP | GO:0004939 | beta-adrenergic receptor activity | 2.0 E-11 | ADRB1, ADRB2 |
| GOTERM_BP | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure | 2.0 E-11 | ADRA1A, ADRA1D |
| GOTERM_BP | GO:0001985 | negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure | 2.0 E-11 | ADRA1A, ADRA1D |