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. 2020 Aug 31;9(2):429–442. doi: 10.1016/j.gendis.2020.08.009

Figure 4.

Figure 4

Ccrl2 deficiency mice showed aggravated VAT inflammation manifested in accumulation of macrophages and increased M1/M2 ratio. (A) FCM analysis of proportion of macrophages in VAT and SAT of mice of different genotypes (n = 6, 8, 8). (B) F4/80 immunofluorescence staining of VAT. (C) ATMs associated inflammation markers in VAT (n = 6 in per group). (D) FCM results of the M1 M2 macrophage ratio of VAT (n = 7, 6, 7). (E) FCM results of the M1 M2 macrophage ratio of SAT (n = 7, 6, 7). Data are expressed as Mean ± SEM,∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.