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. 2022 Feb 14;13:855. doi: 10.1038/s41467-022-28276-x

Fig. 2. Regional association plots for selected top SNPs showing genetic associations with mean-max cIMT.

Fig. 2

A Regional association plot of the FBXL17 region in the combined dataset. B Plot of the SIRPA region in the combined dataset. C Regional association plot of the PROK1 region in the female-specific dataset. D Regional association plot of the LARP6/UACA region female-specific dataset. E Regional association plot of the MAP3K7 region in the male-specific dataset. F Regional association plot of the SNX29 region in the male-specific dataset. For each locus, the plots show the −log10-transformed p-value of each SNP on the y-axis and base-pair positions along the chromosomes on the X-axis. Genes overlapping the locus are displayed below the plot. SNPs are coloured by their LD value r2 (generated from the study population) with the lead SNP in the region shown as a purple diamond.