. 2022 Feb 14;13:855. doi: 10.1038/s41467-022-28276-x

Table 1.

Genome-wide significantly associated SNPs (p < 5E-08) with Mean-Max cIMT for the combined AWI-Gen dataset (n = 7894).

GWAS	rsID	chr	pos	Non-effect allele	Effect allele	MAF	gwasP	Beta	SE	IndSigSNP	Nearest Gene	Genic position
Combined analysis	rs552690895	5	107570359	A	G	0.013	2.50E-08	−0.043	0.008	rs552690895	FBXL17	Intronic
Combined analysis	rs6045318	20	1883451	G	A	0.024	4.70E-08	−0.031	0.006	rs6045318	SIRPA	Intronic
Female-specific	rs115473055	1	111020548	T	C	0.080	1.00E-08	−0.026	0.005	rs115473055	CYMP	Intergenic
Female-specific	rs150840489	15	71088277	A	G	0.037	2.40E-09	−0.051	0.009	rs150840489	RPL29P30	Downstream
Male-specific	rs190770959	16	12158574	T	C	0.015	6.30E-09	−0.056	0.01	rs190770959	SNX29	Intronic
Male-specific	rs147978408	16	12171475	C	T	0.016	6.60E-09	−0.055	0.01	rs190770959	SNX29	Intronic

Adjustment was made for age, sex and 8 PCs for the combined analysis and for age and 5 PCs for sex-specific analysis. Bonferroni correction for genome-wide significance was made (p < 5E-08).

pos position, chr chromosome, rsID single-nucleotide polymorphism, MAF minor allele frequency for the combined sample (7894), beta SNP effect for the combined analysis, SE standard error, gwasP p-value for the association test with BOLT-LMM, IndSigSNP lead SNP for the signal.