Table 2.
Effects of thyme oil and thymol oral supplementation on tumor markers AFP and CA19.9 in serum of DOX-injected rats.
| Groups | Parameters | |||
|---|---|---|---|---|
| AFP (ng/mL) | % change | CA19.9 (U/mL) | % change | |
| Normal | 0.37 ± 0.04 | — | 117.32 ± 2.35 | — |
| DOX-injected control | 1.12 ± 0.12a | +202.70 | 386.90 ± 36.10a | +229.78 |
| DOX-injected group treated with thyme oil | 0.64 ± 0.07ab | -42.86 | 164.30 ± 5.96b | -57.53 |
| DOX-injected group treated with thymol | 0.67 ± 0.08ab | -40.18 | 190.67 ± 14.04ab | -50.72 |
| F-prob. | p < 0.001 | p < 0.001 | ||
| LSD at the 5% | 0.24 | 57.91 | ||
| LSD at the 1% | 0.33 | 78.98 | ||
Data are represented as M ± SE of six rats. aSignificant as compared to normal at p < 0.05. bSignificant as compared to DOX-injected control at p < 0.05. Percentage changes were computed by comparing DOX-injected control with normal and DOX-injected groups treated with thyme oil and thymol with DOX-injected control.