TABLE 2.
Associations between kPCr and mobility (n = 380)
| Cross‐sectional associations between kPCr and mobility at baseline | Longitudinal associations between baseline kPCr and subsequent mobility changes | |||
|---|---|---|---|---|
| β (95% CI) | p‐Value | β (95% CI) | p‐Value | |
| 6‐m usual gait speed | ||||
| Age | −0.039 (−0.050, −0.023) | <0.001 | −0.006 (−0.009, −0.002) | 0.004 |
| kPCr | 0.111 (0.010, 0.211) | 0.031 | 0.036 (0.006, 0.067) | 0.020 |
| 2.5‐min usual gait speed | ||||
| Age | −0.042 (−0.055, −0.029) | <0.001 | −0.004 (−0.008, −0.001) | 0.013 |
| kPCr | 0.143 (0.045, 0.241) | 0.005 | 0.029 (0.002, 0.056) | 0.038 |
| 6‐m rapid gait speed | ||||
| Age | −0.058 (−0.071, −0.046) | <0.001 | −0.002 (−0.005, 0.002) | 0.283 |
| kPCr | 0.040 (−0.052, 0.131) | 0.397 | 0.034 (0.008, 0.060) | 0.011 |
| 400‐m walk time (n = 374) | ||||
| Age | 0.069 (0.057, 0.082) | <0.001 | 0.009 (0.005, 0.012) | <0.001 |
| kPCr | −0.142 (−0.238, −0.045) | 0.004 | −0.042 (−0.067, −0.018) | <0.001 |
Models were adjusted for baseline age, sex, extent of PCr depletion during exercise, and body mass index over time. Values of mobility measures and kPCr were computed as standardized Z scores based on mean and standard deviation at baseline. Bold numbers reflect significant associations at two‐sided p < 0.05.