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. 2021 Nov 25;16(1):171–182. doi: 10.1007/s12072-021-10266-8

Table 2.

The 28-day and 90-day mortality rate in ACLF patients with and without cirrhosis

28-day mortality rate 90-day mortality rate
Cirrhosis Non-cirrhosis OR (95%CI) p-value Cirrhosis Non-cirrhosis OR (95%CI) p-value
Overall 26.5% (169/637) 47.6% (468/984) 2.51 (2.02–3.12)  < 0.001 38.5% (245/637) 57.3% (564/984) 2.15 (1.75–2.63)  < 0.001
ARLD 23.6% (100/423) 49.9% (217/435) 3.22 (2.40–4.31)  < 0.001 35.2% (149/423) 58.4% (254/435) 2.58 (1.96–3.40)  < 0.001
HBV infection 39.8% (39/98) 38.6% (68/176) 0.95 (0.57–1.58) 0.90 46.9% (46/98) 48.9% (86/176) 1.08 (0.66–1.77) 0.80
HCV 10% (1/10) 37.5% (12/32) 5.40 (0.61–48.08) 0.10 30.0non% (3/10) 59.4% (19/32) 3.41 (0.74–15.68) 0/10
NASH 40.5% (15/37) 59.1% (26/44) 2.11 (0.87–5.16) 0.10 67.6% (25/37) 61.4% (27/44) 0.76 (0.31–1.91) 0.56
Cryptogenic 24.3% (9/37) 47.7% (51/107) 2.83 (1.22–6.57) 0.01 32.4% (12/37) 57.9% (62/107) 2.87 (1.31–6.31) 0.007
Other causes 19.2% (5/26) 47.2% (17/36) 3.76 (1.16–12.16) 0.02 34.6% (9/26) 63.9% (23/36) 3.34 (1.16–9.61) 0.02

ARLD alcohol-related liver disease, HBV hepatitis B virus, HCV hepatitis C virus, NASH non-alcoholic steatohepatitis