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. 2022 Feb 14;12:2418. doi: 10.1038/s41598-022-05687-w

Table 2.

Predictors of worsened neuropsychiatric symptoms.

Variable Depression Apathy Delusions Anxiety Irritability
p OR (95% CI) p OR (95% CI) p OR (95% CI) p OR (95% CI) p OR (95% CI)
Survey completion (Days since 100 cases) 0.386 0.99 (0.98–1.01) 0.075 1.01 (0.99–1.03) 0.006 1.02 (1.01–1.04) 0.254 1.01 (0.99–1.02) 0.612 1.00 (0.99–1.02)
Age (Patient) 0.269 1.03 (0.98–1.08) 0.397 1.02 (0.97–1.03) 0.185 1.04 (0.98–1.10) 0.484 1.02 (0.97–1.07) 0.028 1.08 (1.01–1.15)
Sex (Patient)
Male
Female 0.436 1.39 (0.61–3.18) 0.294 0.60 (0.23–1.56) 0.111 0.47 (0.18–1.19) 0.984 0.96 (0.38–2.44) 0.067 0.40 (0.15–1.07)
Country
Australia 0.745 0.80 (0.20–3.15) 0.076 5.64 (0.83–38.10) 0.340 2.01 (0.48–8.37) 0.417 0.56 (0.13–2.30) 0.336 2.06 (0.47–8.96)
Germany 0.141 0.42 (0.13–1.33) 0.000 0.05 (0.01–0.22) 0.100 0.36 (0.11–1.22) 0.068 0.25 (0.06–1.11)
Spain 0.006 6.18 (1.69–22.68)
Region
Urban
Regional 0.097 2.15 (0.87–5.29) 0.001 5.89 (2.04–16.97) 0.174 2.06 (0.73–5.84) 0.508 1.40 (0.52–3.78) 0.987 0.99 (0.34–2.93)
Diagnosis
AD 0.362 0.57 (0.17–1.92) 0.215 0.43 (0.11–1.63) 0.503 1.43 (0.50–4.06) 0.639 1.45 (0.31–6.77)
FTD 0.910 0.93 (0.27–3.27) 0.705 0.81 (0.27–2.42) 0.181 0.39 (0.10–1.56) 0.171 0.39 (0.10–1.51) 0.456 1.84 (0.37–9.07)
Other dementia 0.002 8.39 (2.14–32.88)
Living with
Yes
No 0.002 3.76 (1.61–8.82) 0.477 1.40 (0.56–3.51) 0.015 3.25 (1.25–8.46) 0.002 4.17 (1.70–10.24) 0.399 1.52 (0.58–4.02)
COVID-19 awareness
Yes 0.299 0.54 (0.16–1.74) 0.748 0.82 (0.25–2.69) 0.481 0.64 (0.18–2.24) 0.046 3.64 (1.02–12.95) 0.140 0.39 (0.11–1.36)
No
COVID-19 understanding
None/limited 0.046 3.01 (1.02–8.89) 0.001 7.90 (2.29–27.30) 0.003 6.00 (1.82–19.81) 0.004 5.99 (1.76–16.52) 0.008 5.04 (1.54–16.52)
Moderate/good

Significant values are in bold.

Responses of “unsure” were not included in the regression analyses.