Table 2.
Predictors of worsened neuropsychiatric symptoms.
| Variable | Depression | Apathy | Delusions | Anxiety | Irritability | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | |
| Survey completion (Days since 100 cases) | 0.386 | 0.99 (0.98–1.01) | 0.075 | 1.01 (0.99–1.03) | 0.006 | 1.02 (1.01–1.04) | 0.254 | 1.01 (0.99–1.02) | 0.612 | 1.00 (0.99–1.02) |
| Age (Patient) | 0.269 | 1.03 (0.98–1.08) | 0.397 | 1.02 (0.97–1.03) | 0.185 | 1.04 (0.98–1.10) | 0.484 | 1.02 (0.97–1.07) | 0.028 | 1.08 (1.01–1.15) |
| Sex (Patient) | ||||||||||
| Male | – | – | – | – | – | – | – | – | – | – |
| Female | 0.436 | 1.39 (0.61–3.18) | 0.294 | 0.60 (0.23–1.56) | 0.111 | 0.47 (0.18–1.19) | 0.984 | 0.96 (0.38–2.44) | 0.067 | 0.40 (0.15–1.07) |
| Country | ||||||||||
| Australia | 0.745 | 0.80 (0.20–3.15) | 0.076 | 5.64 (0.83–38.10) | 0.340 | 2.01 (0.48–8.37) | 0.417 | 0.56 (0.13–2.30) | 0.336 | 2.06 (0.47–8.96) |
| Germany | 0.141 | 0.42 (0.13–1.33) | – | 0.000 | 0.05 (0.01–0.22) | 0.100 | 0.36 (0.11–1.22) | 0.068 | 0.25 (0.06–1.11) | |
| Spain | – | – | 0.006 | 6.18 (1.69–22.68) | – | – | – | – | – | – |
| Region | ||||||||||
| Urban | – | – | – | – | – | – | – | – | – | – |
| Regional | 0.097 | 2.15 (0.87–5.29) | 0.001 | 5.89 (2.04–16.97) | 0.174 | 2.06 (0.73–5.84) | 0.508 | 1.40 (0.52–3.78) | 0.987 | 0.99 (0.34–2.93) |
| Diagnosis | ||||||||||
| AD | 0.362 | 0.57 (0.17–1.92) | – | – | 0.215 | 0.43 (0.11–1.63) | 0.503 | 1.43 (0.50–4.06) | 0.639 | 1.45 (0.31–6.77) |
| FTD | 0.910 | 0.93 (0.27–3.27) | 0.705 | 0.81 (0.27–2.42) | 0.181 | 0.39 (0.10–1.56) | 0.171 | 0.39 (0.10–1.51) | 0.456 | 1.84 (0.37–9.07) |
| Other dementia | – | – | 0.002 | 8.39 (2.14–32.88) | – | – | – | – | – | – |
| Living with | ||||||||||
| Yes | – | – | – | – | – | – | – | – | – | – |
| No | 0.002 | 3.76 (1.61–8.82) | 0.477 | 1.40 (0.56–3.51) | 0.015 | 3.25 (1.25–8.46) | 0.002 | 4.17 (1.70–10.24) | 0.399 | 1.52 (0.58–4.02) |
| COVID-19 awareness | ||||||||||
| Yes | 0.299 | 0.54 (0.16–1.74) | 0.748 | 0.82 (0.25–2.69) | 0.481 | 0.64 (0.18–2.24) | 0.046 | 3.64 (1.02–12.95) | 0.140 | 0.39 (0.11–1.36) |
| No | – | – | – | – | – | – | – | – | – | – |
| COVID-19 understanding | ||||||||||
| None/limited | 0.046 | 3.01 (1.02–8.89) | 0.001 | 7.90 (2.29–27.30) | 0.003 | 6.00 (1.82–19.81) | 0.004 | 5.99 (1.76–16.52) | 0.008 | 5.04 (1.54–16.52) |
| Moderate/good | – | – | – | – | – | – | – | – | – | – |
Significant values are in bold.
Responses of “unsure” were not included in the regression analyses.