Amino group substituents are a determining factor for the function of ACF
(A) Structural formulas of ACF and different derivatives of acridine and TOP inhibitors used. Images were taken from https://www.sigmaaldrich.com. (B–G) Relative lncRNA expression levels of BOLA3-AS1 (B), FENDRR (C), H19 (D), HIF1α-AS1 (E), MEG3 (F), and FLJ31356 (G) after treatment with the indicated reagents (16 h, 10 μM) in HUVECs. The CTL was set to 1. n = 3, paired t test. Error bars are defined as mean ± SEM. ∗p < 0.05.