Table 5.

Docking parameters like binding energy and amino acids involved in T-res-HSA and T-res- HSA mutant interaction.

Protein–ligand system	Amino acid residues involved in stabilizing HSA-T-res complex	Binding energy of the complex
(a) T-res-HSA	Ala-215, Ala-210, Phe-211, Ser-202, Val-482, Val-344, Trp-214, Leu-198, Leu-481, Ser-454, Asn-458, Leu-457, Arg-484 and Arg-485	−7.76 kcal mol−1
(b)T-res-HSA (Trp-214 substituted with Gly)	Arg-484, Ser-454, Leu-198, Leu481, Lys-199, Ser-202, Ala-215, Ala-210, Gly-214, Phe-211, Asn-458, Leu-457, Val-344, Val-482, Leu-347	−7.06 kcal mol−1
(c) T-res-HSA (Trp-214 substituted with Val)	Lys-190, Asn-429, Ala-194, Asp-108, Tyr-148, Ala-194, His-146	−6.29 kcal mol−1