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. 2022 Feb 1;9:823900. doi: 10.3389/fmed.2022.823900

Table 1.

Demographic and clinical characteristics of the immigrant and native-born IBD population in Spain.

Immigrants Natives P -value
(n = 1,864) (n = 11,660)
Gender, female (n,%) 936 (50.2) 5444 (46.7) 0.005
Mean current age (SD) 45.3 (12.6) 54.5 (16.0) <0.001
Mean age at IBD diagnosis 31.2 (12.0) 36.5 (15.6) <0.001
Mean duration of disease (SD) 14.0 (7.2) 18.0 (8.7) <0.001
Smoking habit
no (n,%) 1181 (69.3) 6952 (59.5) <0.001
yes (n,%) 296 (17.4) 2227 (19.1)
Ex (n,%) 227 (13.3) 2508 (21.5)
Crohn's disease (n,%) 777 (41.8) 4755 (40.8) 0.068
Ulcerative colitis (n,%) 1029 (55.4) 6665 (57.2)
Unclassified IBD (n,%) 52 (2.8) 240 (2.1)
Crohn's age at diagnosis
A1 (<16y) (n,%) 67 (8.6) 275 (5.8) <0.001
A2 (16-40y) (n,%) 586 (75.3) 3223 (67.8)
A3 (>40y) (n,%) 125 (16.1) 1257 (26.4)
Crohn's location
L1 (ileal) (n,%) 154 (28.5) 1025 (28.4) 0.368
L2 (colonic) (n,%) 112 (20.7) 640 (17.7)
L3 (ileocolonic) (n,%) 233 (43.1) 1636 (45.3)
L4 (upper GI) (n,%) 42 (7.8) 308 (8.5)
Crohn's behavior
B1 (inflammatory) 482 (63.9) 2744 (57.7) 0.002
B2 (stricturing) (n,%) 144 (19.1) 1158 (24.4)
B3 (perforating) (n,%) 128 (17.0) 853 (17.9)
Perianal perforating (n;%) 242 (13.7) 1776 (15.4) 0.069
Ulcerative colitis extent
Proctitis (n,%) 186 (29.7) 1478 (31.9) 0.031
Left sided colitis (n,%) 357 (57.0) 2689 (58.1)
Extensive colitis (n,%) 83 (13.3) 459 (9.9)
Extraintestinal manifestations (n;%) 318 (18.9) 1275 (10.9) <0.001
Family history of IBD (n,%) 155 (9.4) 1676 (14.3) <0.001