Table 1.
Inhibitor Susceptibilities of Ugandan Plasmodium falciparum Isolates and Laboratory Control Strains
| Ugandan Isolates | Laboratory Strains | ||||
|---|---|---|---|---|---|
| Inhibitor | Na | Median IC50 (nM) | IC50 Range (nM) | 3D7 (Median IC50, nM (n)) | Dd2 (Median IC50, nM (n)) |
| Pyrimethamine | 528 | 42 100 | 998–200 000 | 27 (40) | 28 900 (40) |
| Cycloguanil | 151 | 1200 | 450–7300 | 4.8 (9) | 1400 (8) |
| Proguanil | 141 | 13 000 | 190–61 000 | 1600 (8) | 1700 (7) |
| P218 | 545 | 0.6 | 0.1–14 | 0.4 (38) | 0.7 (39) |
Abbreviations: IC50, half-maximal inhibitory concentrations.
aTotal number of isolates tested.