REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
cyclin C	ThermoScientific	PA5-16227; RRID:AB_10982613
Alexa Fluor 488-conjugated secondary antibody	ThermoScientific	A11008; RRID:AB_143165
alkaline phosphatase-conjugated rabbit secondary antibody	Abcam	ab97061; RRID:AB_10680575
LDHA	Santa Cruz Biotechnology	SC-137243; RRID:AB_2137192
β-actin	Merck	A1978; RRID:AB_476692
dsDNA	Dev. Studies Hybridoma Bank	RRID:AB_10805293
Chemicals, peptides, and recombinant proteins
H2O2	ACS Chemical	UN2014
Pifithrin μ	TGI Chemica	P2048
carbonyl cyanide p-trifluoromethoxyphenylhydrazone	Cayman Chemical	15218
Oligomycin	Sigma	49455
Rotenone	Sigma	R8875
Antimycin A	Sigma	R8875
MitoTempo	Sigma	SML0737
Actinomycin D	Cayman Chemical	11421
Tetramethylrhodamine (TMRM)	Invitrogen	I34361
Critical commercial assays
Annexin V Cell Death Assay	BD Biosciences	556419
Bradford Protein	Bio-Rad	5000001
Experimental models: Cell lines
MED13LS1497F/+ human dermal fibroblast	Center for Molecular Medicine UMC Utrecht Netherlands	N/A
MED13L+/+ human dermal fibroblast corrected allele	This study	N/A
WI-38	ATCC	CCL-75
Experimental models: Organisms/strains
XL-1 Blue Escherichia coli	Agilent	200249
Oligonucleotides
MED13L exon 20, Forward AGCCTAGTCCAAGTTTTAGAGAG	This study	N/A
MED13L exon 20, Reverse AAACTGCCCAGAACACCAAACTGG	This study	N/A
M13 Sequencing Primer Forward TGTAAAACGACGGCCAGT	This study	N/A
M13 Sequencing Primer, Reverse CAGGAAACAGCTATGAC	This study	N/A
MED13L intron19-20, Forward CGATCAGCATACTCACTGCTTCAG	This study	N/A
MED13L intron19-20, Reverse GTCTCCTTTCAGACTGATTCCATG	This study	N/A
mtMinArc Forward CTAAATAGCCCACACGTTCCC	mt 16,528 – 16,548	(Phillips et al., 2014)
mtMinArc Reverse AGAGCTCCCGTGAGTGGTTA	mt 23-42	(Phillips et al., 2014)
Fβ2M Forward GCTGGGTAGCTCTAAACAATGTATTCA	Chr15 15,798,932 – 15,798,95	(Phillips et al., 2014)
Fβ2M Reverse CCATGTACTAACAAAT GTCTAAAATGGT	Chr15 15,798,999 – 15,799,02	(Phillips et al., 2014)
Recombinant DNA
pGL3-U6-sgRNA-PGK-puromycin	Addgene	51133
pTE4398	Addgene	74042
pX330S-2	Addgene	58778