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. 2021 Dec 22;2(2):100092. doi: 10.1016/j.xjidi.2021.100092

Table 4.

The Serum Phospholipids Being Associated with the Risk of AD

Variable OR AD
Sph 1.142343555
LPE(20:4) 1.002415184
LPC(16:1) 1.001474071
PC(36:0) 1.000258849
PC(30:0) 1.000220845
LPC(16:0) 1.000218341
PC(38:3) 1.000179719
SM(24:1) 1.000111326
SM(16:0) 1.000056987
PC(32:1) 1.000043308
PC(38:2) 1.000011827
SM(12:0) 1
SM(14:0) 1
SM(18:1) 1
SM(20:0) 1
SM(22:0) 1
SM(24:0) 1
PC(28:0) 1
PC(30:1) 1
PC(34:1) 1
PC(34:2) 1
PC(36:1) 1
PC(36:2) 1
PC(36:4) 1
PC(38:1) 1
PC(38:4) 1
LPC(18:0) 1
LPC(18:1) 1
LPC(20:1) 1
LPC(20:3) 1
LPE(16:0) 1
LPE(18:1) 1
LPE(18:2) 1
Lyso-PAF 1
LPC(18:2) 0.999835522
SM(18:0) 0.999788959
PC(32:0) 0.99943743
LPC(20:4) 0.998199605
Cer(16:0) 0.976745322
LPE(18:0) 0.954168832

Abbreviations: AD, atopic dermatitis; Cer, ceramide; LPC, lysophosphatidylcholine; LPE, lysophosphatidylethanolamine; PAF, platelet-activating factor; PC, phosphatidylcholine; SM, sphingomyelin; Sph, sphingosine.

We sought the serum phospholipids being associated with the risk of AD with L1 penalized logistic regression between AD and non-AD, which includes healthy controls and those with non-AD with atopic comorbidities.