REAGENT or RESOURCE	SOURCE	IDENTIFIER
Critical commercial assays
Mouse Insulin ELISA kit	Mercodia	10-1247-01
Pierce BCA protein assay kit	Thermo Fisher Scientific	23225
RNeasy kit	Qiagen	74104
iScript cDNA synthesis kit	BIO-RAD	1708890
TruSeq Stranded mRNA	Illumina	20020595
Deposited data
RNA-seq data	This paper	GEO: GSE194193
Experimental models: Organisms/strains
Mouse: C57BL/6NTac	Taconic	B6-M
Mouse: I-Pax7CreERT2-R26RtdTomato+	Own breeding	N/A
Oligonucleotides
Primer 18s Forward	This paper	AGTCCCTGCCCTTTGTACACA
Primer 18s Reverse	This paper	GATCCGAGGGCCTCACTAAAC
Primer Gapdh Forward	This paper	GCACAGTCAAGGCCGAGAAT
Primer: Gapdh Reverse	This paper	GCCTTCTCCATGGTGGTGAA
Primer Tbp Forward	This paper	ACCCTTCACCAATGACTCCTATG
Primer Tbp Reverse	This paper	TGACTGCAGCAAATCGCTTGG
Primer Nmrk1 Forward	This paper	AGAGCTTGCAGAAGCACCTTCC
Primer Nmrk1 Reverse	This paper	CATCCAACAGGAAACTGCTGACA
Software and algorithms
OTOFControl	Bruker Daltonics	v6.0
Compass HyStar	Bruker Daltonics	v5.0
MzMine	Pluskal et al. (2010)	v2.53
STAR aligner	Dobin et al. (2013)	v2.7.3a
FeatureCounts	Liao et al. (2014)	v2.0.0
edgeR	Robinson et al. (2010)	v3.30.3
JMP	SAS	Pro 15
Prism	GraphPad	v8.4.3
Other
Mouse jugular vein catheter	Instech	C20PU-MJV1458
Vascular Access Button	Instech	VABM1B/25
Handling tool for magnetic mouse Vascular Access Buttons	Instech	VABMG
Pinport Injectors	Instech	PNP3M-50