Table 3. Reported coronavirus disease 2019 vaccine adverse event grouped by gender.
| Characteristic | Gender | p-value | |||
|---|---|---|---|---|---|
| Male | Female | Unknown | |||
| Age (yr) | 0.829 | ||||
| 12–55 | 29 (60.4) | 97 (64.2) | 1 (100.0) | ||
| >55 | 19 (39.6) | 54 (35.8) | 0 | ||
| Vaccine | 0.057 | ||||
| Pfizer-BioNTech | 42 (87.5) | 139 (92.1) | 1 (100.0) | ||
| Moderna | 2 (4.2) | 11 (7.3) | 0 | ||
| Janssen | 4 (8.3) | 1 (0.7) | 0 | ||
| Local reaction | 4 (8.3) | 13 (8.6) | 0 | 0.601 | |
| Erythema at the injection site | 0 | 1 (0.7) | 0 | ||
| Pruritus at the injection site | 0 | 1 (0.7) | 0 | ||
| Pain at the injection site | 3 (6.3) | 7 (4.6) | 0 | ||
| Reaction at the injection sitea) | 1 (2.1) | 4 (2.6) | 0 | ||
| Systemic reaction: top 10 systemic reaction | 0.002* | ||||
| Fatigue/asthenia | 17 (35.4) | 61 (40.4) | 0 | ||
| Pyrexia/increased body temperature | 16 (33.3) | 43 (28.5) | 0 | ||
| Headache | 13 (27.1) | 58 (38.4) | 0 | ||
| Pain (general)/pain in extremity/myalgia | 19 (39.6) | 44 (29.1) | 0 | ||
| Chills | 12 (25.0) | 51 (33.8) | 0 | ||
| Arthralgia/joint swelling/joint stiffness/joint range of motion decreased/musculoskeletal stiffness | 10 (20.8) | 18 (11.9) | 0 | ||
| Dizziness | 4 (8.3) | 18 (11.9) | 0 | ||
| Nausea | 3 (6.3) | 17 (11.3) | 0 | ||
| Peripheral swelling/eye swelling/face swelling/pharyngeal swelling/oedema/lip swelling/swelling | 0 | 15 (9.9) | 0 | ||
| Feeling abnormally/hot or cold | 1 (2.1) | 11 (7.3) | 0 | ||
Values are presented as number (%). Data extracted from the Vaccine Adverse Event Reporting System and stratified by gender [4].
*p<0.05 (statistically significant). a)Injection or vaccination site reaction included multiple parameters (i.e., pruritus, pain, swelling, redness, bruising, warmth, irritation, and/or erythema).