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. 2022 Jan 31;11(1):104–115. doi: 10.7774/cevr.2022.11.1.104

Table 6. Top five systemic reactions stratified by the three administered vaccines and age.

Vaccines by age (yr) Total p-value
Pfizer (n=182) Moderna (n=13) Janssen (n=5)
12.55 >55 12.55 >55 12.55 >55
Headache 0.110
No 74 39 8 3 2 3 129
Yes 42 27 1 1 0 0 71
Total 116 66 9 4 2 3 200
Fatiguea) 0.023*
No 77 30 7 4 1 3 122
Yes 39 36 2 0 1 0 78
Total 116 66 9 4 2 3 200
Chills 0.070
No 74 46 8 4 2 3 137
Yes 42 20 1 0 0 0 63
Total 116 66 9 4 2 3 200
Pyrexiab) 0.051
No 72 53 9 2 2 3 141
Yes 44 13 0 2 0 0 59
Total 116 66 9 4 2 3 200
Painc) 0.133
No 74 47 7 4 2 3 137
Yes 42 19 2 0 0 0 63
Total 116 66 9 4 2 3 200

Data extracted from the Vaccine Adverse Event Reporting System database [4].

*p<0.05 (statistically significant). a)Fatigue and asthenia. b)Pyrexia and increased body temperature. c)Pain, pain in extremity, and myalgia grouped together.