Fig. 4.
Properties of the characteristic parameters TC and CAS in TFCRs. (A) Correlation analysis of the TF complexity and chromatin accessibility score in TFCRs (R2 = 0.05). Boxplot shows (B) the distribution of score in different groups obtained by grouping the TF complexity of TFCRs with an interval value of 10. (C-D) The gene expression levels in different groups in ATAC-seq peaks classified by CAS and TFCRs classified by TC. The upper and lower lines above and below the boxes are the whiskers. (E) Barplot shows the mutation distribution of TFCR with promoter and TFCR without promoter. (F) The line graph shows the mutation rate of TFCRs in gene promoters (CAS: Darkblue; TC: Darkred) classified by TC or CAS. (G-H) Barplots show the proportion of reported cancer driver genes distributed in different classification of TC and CAS.