Fig. 4.

Biofilm disruption of S. aureus NCIM 5021 and S. aureus J6 using antibiotic combinations. Twenty-four-hour-old biofilms were treated with a combination of antibiotics for 24 h. Ciprofloxacin plus daptomycin against NCIM 5021 (A), ciprofloxacin plus vancomycin against NCIM 5021 (B), daptomycin plus tobramycin against NCIM 5021 (C), and daptomycin plus tobramycin against J6 (D) applied at 1X, 10X, and 100X MIC in combination. The data shown are the mean values of percent disruption (n = 3); the error bars indicate standard deviation. (C-ciprofloxacin, D-daptomycin, T-tobramycin, V-vancomycin).