Table 1.
Patient characteristics at first hospital stay (N = 3650 patients).
| OverallN (%) | Surgery group N (%) | Chemotherapy group N (%) | Best supportive care group N (%) | |
|---|---|---|---|---|
| Global population with iCCA | 3 650 (100) | 410 (11·2%) | 869 (23·8) | 2 371 (65·0%) |
| Gender | ||||
| Male | 2 082 (57·0) | 257 (62·7%) | 513 (59·0) | 1 312 (55·3) |
| Female | 1 568 (43·0) | 153 (37·3%) | 356 (41·0) | 1 059 (44·7) |
| Age (years) | ||||
| Mean | 72·0 | 66·0 | 66·8 | 74·9 |
| Median [Min / Max] | 73·0 / 23·0 / 101·0 | 67·0 / 23·0 / 95·0 | 68·0 / 27·0 / 92·0 | 77·0 / 23·0 / 101·0 |
| Age in classes | ||||
| < 50 years | 35 (6·7) | 50 (6·2) | 73 (3·1) | 158 (4·3) |
| 50–69 years | 265 (51·1) | 414 (51·0) | 614 (26·5) | 1293 (35·4) |
| 70–79 years | 168 (32·4) | 259 (31·9) | 642 (27·7) | 1069 (29·3) |
| ≥ 80 years | 51 (9·8) | 89 (11·0) | 990 (42·7) | 1130 (31·0) |
| Symptoms at inclusion | ||||
| Jaundice (1) | 639 (17·5) | 36 (8·8) | 70 (8·1) | 533 (22·5) |
| Angiocholitis (2) | 273 (7·5) | 27 (6·6) | 21 (2·4) | 225 (9·5) |
| Ascites (3) | 444 (12·2) | 31 (7·6) | 34 (3·9) | 379 (16·0) |
| Anaemia (4) | 596 (16·3) | 69 (16·8) | 70 (8·1) | 457 (19·3) |
| Distant metastasis Liver metastasis |
1 290 (35·3) 686 (18·8) |
70 (17·1) 21 (5·1) |
331 (38·1) 169 (19·4) |
889 (37·5) 496 (20·9) |
| Peritoneal metastasis Lung metastasis Lymph node metastasis |
389 (10·7) 325 (8·9) 264 (7·2) |
14 (3·4) 11 (2·7) 27 (6·6) |
81 (9·3) 71 (8·2) 99 (11·4) |
294 (12·4) 243 (10·2) 138 (5·8) |
| Bone metastasis | 245 (6·7) | 12 (2·9) | 61 (7·0) | 172 (7·3) |
| Patients hospitalized in their region of residence (at S1) | 3 428 (93·9) | 367 (89·5) | 819 (94·2) | 2 242 (94·6) |
iCCA : intra-hepatic cholangiocarcinoma; (1) R17 (2) K803, K830 (3) R18 (4) D50, D510, D519, D52, D539, D598, D599, D62, D630, D638, D648, D649
All statistical tests between columns are statistically significant at 0·05%.