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. 2022 Jan 19;27:998–1009. doi: 10.1016/j.omtn.2022.01.010

Figure 4.

Figure 4

CP-bi-apt enhances the killing effect of NK cells

(A–C) Flow cytometry analysis of the cell activity of (A) QSG-7701, (B) HeLa, and (C) SMMC-7721 in the presence of NK cells and different aptamers. The above experiments were all gated on CD16 (−) cells by using antigen-presenting cell (APC)-conjugated anti-CD16 antibody. (D and E) The analysis of IFN-γ, TNF-α, granzyme B, and perforin in supernatants of (D) HeLa cells and (E) SMMC-7721 cells after indicated treatment is shown; n = 3.