Table 2.

Triage tool diagnostic accuracy statistics (95% CI) for predicting any adverse outcome

Tool	N*	n (%) adverse outcome†	C-statistic	Threshold	n (%) above threshold	Sensitivity	Specificity	PPV	NPV
CRB-65	7469	1315 (18)	0.79 (0.78 to 0.80)	>0	4010 (54)	0.89 (0.88 to 0.89)	0.54 (0.53 to 0.54)	0.29 (0.29 to 0.30)	0.96 (0.95 to 0.96)
NEWS2	7433	1315 (18)	0.80 (0.78 to 0.81)	>1	5574 (75)	0.96 (0.96 to 0.96)	0.30 (0.29 to 0.30)	0.23 (0.22 to 0.23)	0.97 (0.97 to 0.97)
PMEWS	7460	1315 (18)	0.81 (0.80 to 0.83)	>2	5352 (72)	0.98 (0.97 to 0.98)	0.34 (0.33 to 0.34)	0.24 (0.24 to 0.24)	0.99 (0.98 to 0.99)
PRIEST	7471	1315 (18)	0.83 (0.82 to 0.84)	>4	4932 (66)	0.97 (0.97 to 0.97)	0.41 (0.40 to 0.41)	0.26 (0.25 to 0.26)	0.98 (0.98 to 0.99)
WHO	7471	1315 (18)	0.64 (0.64 to 0.65)	>0	5539 (74)	0.98 (0.97 to 0.98)	0.31 (0.30 to 0.31)	0.23 (0.23 to 0.24)	0.98 (0.98 to 0.99)

*Patients with less than three parameters were excluded from analysis when estimating performance.

†Totals rounded to nearest 5.

NEWS2, National Early Warning Score, version 2; NPV, negative predictive value; PPV, positive predictive value.