Table 2.
Treatment | Visit | Estimated mean (95% CI) | Time | Relative change (95% CI) | P value* |
Famotidine | Day 1 | 152.4 (111.0 to 209.4) | |||
Day 7 | 171.5 (124.3 to 236.8) | Day 7 vs Day 1 | 0.13 (−0.02 to 0.29) | 0.088 | |
Day 14 | 142.5 (102.8 to 197.5) | Day 14 vs Day 1 | −0.07 (−0.19 to 0.08) | 0.361 | |
Day 28 | 103.2 (74.7 to 142.4) | Day 28 vs Day 1 | −0.32 (−0.41 to −0.23) | <0.0001 | |
Placebo | Day 1 | 141.6 (102.9 to 194.9) | |||
Day 7 | 170.6 (123.8 to 235.2) | Day 7 vs Day 1 | 0.21 (0.05 to 0.38) | 0.008 | |
Day 14 | 129.7 (93.7 to 179.4) | Day 14 vs Day 1 | −0.08 (−0.21 to 0.06) | 0.226 | |
Day 28 | 95.5 (68.9 to 132.5) | Day 28 vs Day 1 | −0.33 (−0.42 to −0.22) | <0.0001 |
*P values were based on t-test from a linear mixed model.