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. 2022 Feb 9;14:59–72. doi: 10.2147/JEP.S343735

Table 5.

Antihyperglycemic effect of hydromethanolic crude root extract of D. barnimiana in streptozocin-induced diabetic mice

Group Blood glucose (mg/dL) at weekly intervals
Day 0 Day 7 Day 14 Day 21 Day 28
DW10 277.17±2.00ε* 277.83±2.85ε* 275.18±2.34ε* 271.97±2.55ε* 268.57±1.64ε*
DB100 282.83±3.21ε* 275.65±2.62**β*ε* 268.22±3.10*^β*ε* 259.27±1.84α^*β*ε* 255.41±0.78α**β*ε*
DB200 279.02±6.39ε* 256.16±3.38α**β*ε* 252.56±3.06α**β*ε* 251.01±2.86α**β*ε* 248.69±2.86α**β*ε*
DB400 276.50±2.51ε* 220.59±1.89α*β*ε* 216.38±2.13α*β*ε* 214.43±1.98α*β*ε* 214.07±2.03α*β*ε*
Glc5 276.45±3.34ε* 185.56±2.65α*ε* 178.82±2.47α*ε* 165.94±1.75α*ε* 163.75±1.69α*ε*
NC 129.93±0.75α* 128.67±0.38α* 127.57±0.24α* 126.08±0.54α* 125.56±0.62α*

Notes: Values expressed as means ± SEM (n=6) and analyzed by one-way ANOVA followed by post hoc Tukey tests. αCompared to negative control; compared to DB200 mg/kg; compared to DB400 mg/kg; βcompared to Glc5; εcompared to normal control. ^P<0.01; *P<0.001.

Abbreviations: DB, Dorstenia barnimiana; DW, distilled water; Glc, glibenclamide; NC, normal control (pretreatment significantly brought down the volume of BGL).